Postpartum Hypercalcemia Secondary to a Neuroendocrine Tumor of Pancreas; a Case Report and Review of Literature

Authors

  • Ali A Ghazi Research Institute for Endocrine Sci-ences, Taleghani General Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Atieh Amouzegar Research Institute for Endocrine Sci-ences, Taleghani General Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Farrokh Tirgari Department of Pathology, Imam Kho-meini Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Hamid Attarian Department of Internal Medicine, Ta-leghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Hossein Nejad Gashti Department of Internal Medicine, Hashemi Nejad Hospital, Iran University of Medical Sciences, Tehran, Iran
  • Iranpour Boustani Department of Surgery, Kasra General Hospital, Tehran Iran
  • Kalman Kovacs Department of Laboratory Medicine, Saint Michael’s Hospital, University of Toronto, Toronto Ontario, Canada
  • Marina Pourafkari Department of Radiology, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Siavash Ghazi Department of Internal Medicine, Ta-leghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Taher Sabetian Department of Obstetrics and Gynechology, Kasra General Hospital, Tehran, Iran
Abstract:

Parathyroid hormone-related protein producing pancreatic neuroendocrine tumors have been infrequently reported. Herein, we report a case of an Iranian woman who had such a tumor during pregnancy, and gave birth to a female neonate with esophago-tracheal fistula and imperforated anus. Hypercalcemia was diagnosed at postpartum because of elevated serum calcium levels in the neonate and neurologic deterioration of the mother. Extensive literature review revealed 42 cases with pancreatic neuroendocrine tumors and hypercalcaemia. The clinical and laboratory findings of such patients are reviewed in this manuscript.

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Journal title

volume 36  issue 3

pages  217- 221

publication date 2011-09-01

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